Ginger, Zingiber officinale Roscoe, is a favorite food spice and has a long history of usage in traditional medicine for treating numerous disease symptoms. It is packed with nutrients and bioactive elements that have significant benefits for your body and brain.
Age-related neurological diseases (ANDs), including neurodegenerative diseases, are multifactorial diseases with a risk that develops with aging. ANDs are generally characterized by most common neuropathological conditions of the central nervous system, such as neuroinflammation, oxidative stress, and protein misfolding.
The structure-activity relationships of ginger phytochemicals confirm that ginger can be used to treat ANDs by targeting various ligand sites. The research shows that ginger and its elements, such as 6-shogaol, 6-gingerol, 6-paradol, dehydrozingerone, and zingerone, are effective for improving the neurological symptoms and pathological conditions of ANDs by modulating cell death or cell survival indicating molecules. From this report, we conclude that the active ingredients in ginger have therapeutic potential in ANDs.
Ginger and Testosterone.
Enhancing and preserving testosterone production is one target for many scientists because of its important role as a primary sex hormone in males. The mechanisms by which this happens mainly by enhancing luteinizing hormone (LH) production, improving the level of cholesterol in the testes, decreasing oxidative stress and lipid peroxidation in the testes, enhancing the activity of the antioxidant enzymes, increasing blood flow in the testes, increasing testicular weight, normalizing blood glucose, and recycling testosterone receptors.
A systematic review of the anti-obesity and weight lowering effect of ginger.
Lately, the beneficial results of ginger on obesity is taken into consideration. Ginger could change obesity through various potential mechanisms, including increasing thermogenesis, suppression of lipogenesis, inhibition of intestinal fat absorption, and regulating appetite. This study report presents some convincing evidence to support the efficacy of ginger in obesity management.
Ginger for nausea and vomiting of pregnancy.
In the first trimester, ginger might improve nausea and vomiting by about 4 points on a 40-point scale or stop vomiting for 1 in 3 women at six days. The most extensive study suggests no increase in fetal malformations or stillbirths.
Beneficial effects of ginger on obesity and metabolic syndrome.
Ginger (Zingiber officinale Roscoe, Zingiberaceae) has been documented to ameliorate hyperlipidemia, hyperglycemia, oxidative stress, and inflammation. This statement concentrates on recent findings regarding the beneficial effects of ginger on obesity and discusses its potential mechanisms of action.
Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea.
The meta-analysis of these data showed an important effect of ginger in decreasing PVAS in subjects having primary dysmenorrhea.
Collectively these RCTs give suggestive evidence for the effectiveness of 750-2000 mg ginger powder in the first 3-4 days of the menstrual cycle for primary dysmenorrhea.
Ginger As alternative for the prevention of postoperative nausea and vomiting.
Postoperative nausea and vomiting (PONV) is a distressing result related to surgeries. Traditionally, ginger has been practiced in the treatment of nausea and vomiting for thousands of years.
Ten randomized trials, including a total of 918 patients, were pooled for the statistical report. The present meta-analysis confirms that ginger has a significant effect on the severity of Postoperative nausea and vomiting.
According to our precise meta-analysis ginger is safe and well tolerated, and reduces the severity of PONV, and may lower the incidence of postoperative nausea and vomiting, which in turn may decrease antiemetic drug demand, implying that ginger may be a useful alternative to antiemetic medications to relieve PONV.
Ginger for prevention or treatment of drug-induced nausea and vomiting.
Various studies have evaluated the effects of ginger in prevention and control of nausea and vomiting in different conditions such as pregnancy, post-operation, and chemotherapy. Ginger showed encouraging and winning effects in preventing postoperative nausea and vomiting at least as add-on therapy.
Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine.
This research aims to evaluate the effectiveness of ginger in the ablation of the common migraine attack in comparison to sumatriptan therapy. In this double-blinded randomized clinical trial, 100 patients who had acute migraine without aura were randomly allocated to receive either ginger powder or sumatriptan. It reveals that the effectiveness of ginger powder in the treatment of common migraine attacks is statistically comparable to sumatriptan. The best thing is that ginger also poses a better side effect profile than sumatriptan.
A review of the gastroprotective effects of ginger.
The rhizomes of Zingiber officinale Roscoe (Zingiberaceae) have been used since ancient times in the various traditional methods of medicine to treat arthritis, rheumatism, sore throats, sprains, muscular aches, dementia, pains, cramps, hypertension, fever, infectious diseases, catarrh, gingivitis, toothache, asthma, nervous diseases, stroke and diabetes.
Ginger is also used as a home remedy and is of extensive value in treating various gastric ailments like constipation, dyspepsia, belching, gastritis, epigastric discomfort, bloating, gastric ulcerations, indigestion, nausea and vomiting, and scientific researches have validated the ethnomedicinal uses.
Ginger has been verified to possess free radical scavenging, antioxidant; inhibition of lipid peroxidation and that these features might have contributed to the observed gastroprotective effects.
Protective and therapeutic potential of ginger extract and -gingerol in cancer.
Natural dietary agents have attracted considerable attention due to their role in advancing health and decreasing the risk of diseases including cancer. -Gingerol constitutes the most pharmacologically active among such compounds. This concludes that ginger derivatives, in the form of an extract or isolated compounds, exhibit relevant antiproliferative, antitumor, invasive, and anti-inflammatory activities.
The Effects of Pre-Exercise Ginger Supplementation on Muscle Damage and Delayed Onset Muscle Soreness.
Ginger possesses analgesic and pharmacological characteristics mimicking non-steroidal anti-inflammatory medications. In conclusion, 4 g of ginger supplementation may be consumed to accelerate recovery of muscle strength following intense exercise but does not affect indicators of muscle damage or Delayed Onset Muscle Soreness.
Antioxidant activities of ginger extract and its constituents toward lipids.
Lipid oxidation-a leading cause of food product deterioration-necessitates the use of food additives to inhibit food oxidation. Ginger extract (GE) has been stated to possess antioxidant properties. Overall, Ginger extract showed the strongest dose-dependent antioxidant characteristics, especially at high temperatures, thereby demonstrating that ginger extract can be used as a natural antioxidant in lipid-containing processed foods.
Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer.
Gastrointestinal (GI) cancer, a cancer of different organs of the digestive system, is one of the most common cancers around the globe.
Ginger (Zingiber officinale) is one of the most widely accepted natural products consumed as a spice and medicine for treating nausea, dysentery, heartburn, flatulence, diarrhea, loss of appetite, infections, cough, and bronchitis. Also, several experimental studies showed that ginger and its active elements, including 6-gingerol and 6-shogaol exert anticancer activities against GI cancer.
Prevention of allergic rhinitis by ginger.
Immunoglobulin E (IgE)-mediated hypersensitivity is central to the pathogenesis of asthma, hay fever, and other allergic diseases. Therefore, our results confirm that 6-gingerol suppresses cytokine production for T cell activation and proliferation, thereby not causing B cell and mast cell activation and resulting in prevention or alleviation of allergic rhinitis symptoms.
Ginger prevents severe damage to the lungs due to hyperoxia and inflammation
Hyperoxia- and inflammation-induced lung injury is a basic cause of the development of bronchopulmonary dysplasia (BPD) in premature newborns. Ginger efficiently reduced lung damage and preserved the lungs from severe damage due to hyperoxia and inflammation. Therefore, ginger may be an alternative choice for the treatment of bronchopulmonary dysplasia.
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