<p>Trimethylamine N-oxide (TMAO) is a dietary byproduct
that is created by gut bacteria during digestion. The element is derived in
part from nutrients that are bountiful in red meat. ;</p>



<p>High saturated fat levels in red meat have long been identified to contribute to heart disease, the head reason for death in the United States. An expanding number of researches have classified TMAO as another culprit.</p>
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<figure class="wp-block-image size-large"><img src="https://topnaturalremedy.com/wp-content/uploads/2019/12/red-meat-heart-issue-1024x576.png" alt="" class="wp-image-2235"/></figure>



<p>The precise mechanisms by which TMAO may induce heart
disease is complicated. Earlier research has shown that TMAO enhances
cholesterol levels in the artery wall. ;</p>



<p>Researches also advise that the chemical interacts
with platelets—blood cells that are accountable for normal clotting responses—to
increase the risk for clot-related results such as stroke and heart attack.</p>



<p>To examine the effects of dietary protein on TMAO
production, a research team directed by Dr. Stanley L. Hazen at the Cleveland
Clinic enrolled 113 healthy men and women in a clinical trial. The participants
were given three diets for thirty days in random order.</p>



<p>All meals were served for them, with 25% of calories
from protein. The dietary proteins came from either white meat, red meat, or
non-meat sources. The study was widely supported by NIH’s National Heart, Lung,
and Blood Institute (NHLBI). Results were published on December 10, 2018,
in ;<em>European Heart Journal</em>.</p>
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<p>When on the red meat diet, the participants ate
roughly the equivalent of two quarter-pound beef patties or 8 ounces of steak
daily.</p>



<p>After thirty days on this diet, blood levels of TMAO
were three times higher than when participants were on the diets based on
either white meat or non-meat protein sources.</p>



<p>Half of the participants were also set on
high-saturated fat versions of the three diets. The diets all had the same
amounts of calories. The researchers discovered that saturated fat had no
additional effect on TMAO levels.</p>



<p>Importantly, the TMAO gains were reversible. When the
participants ended the red meat diet and consumed either the white meat or
non-meat diet for another month, their TMAO levels reduced significantly.</p>



<p>“This study exposes for the first time what an
important effect changing your diet has on levels of TMAO, which is
increasingly associated with heart disease,” Hazen says.</p>



<p>“These conclusions reinforce current dietary
recommendations that encourage all ages to follow a heart-healthy consumption
plan that limits red meat,” says nutrition researcher Dr. Charlotte Pratt, the
NHLBI project officer for the study. ;</p>



<p><strong><em>“This means consuming a variety of foods, including more fruits, vegetables, whole grains, low-fat dairy foods, and plant-based protein sources such as peas and beans.”</em></strong>
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<p><strong>Source:</strong> ;<a rel="noreferrer noopener" href="https://www.nih.gov/news-events/nih-research-matters/eating-red-meat-daily-triples-heart-disease-related-chemical" target="_blank">NIH</a>
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